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10X Chromium Controller Single Cell System
The 10x Chromium Controller is a benchtop single cell library preparation system. The platform utilises advanced microfluids to generate tens of thousands of single cell partitions, each containing an identifying barcode for downstream analysis. Partitioning events occur on a microfluidic chip in the presence of barcoded gel beads and oil to create GEMs (Gel Bead in EMulsion). Up to 8 samples can be run simultaneously per chip.
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Accuri C6
The Accuri C6 system offers a 488nm laser and a 633nm laser, 4-colour detector system with the ability to compensate between all 4 detectors. Optical filters are optimised for the use of FITC, PE, ECD/PI, PeCy5 and PeCy7 fluorochrome conjugates with a range of between 488nm - 800nm. This also includes dyes such as GFP, RFP, PerCp and APC derivatives.
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Agilent Bioanalyser
"The Agilent 2100 Bioanalyzer is a microfluidics-based platform for sizing, quantification and quality control of RNA and DNA. It utilises microchannel electrophoretic separation to produce a rapid and sensitive measure of nucleic acid quality and size. The Bioanalyzer software creates a graph called an electropherogram, which diagrams fluorescence over time as molecules are pulsed through the separation channel."
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Agilent Tapestation
The 4200 TapeStation system is a high-throughput automated electrophoresis platform for nucleic acid sample quality control. It allows fully automated, easy, and reliable analysis of DNA and RNA using convinent, pre-prepared Screen Tape. Agilent offers a variety of ScreenTape Assays for the Agilent TapeStation systems. The Genomics Core stocks a variety of Screen Tape in-house.
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Anaerobic Chamber [aka Ariel]
Anaerobic chamber for the growth of anaerobic cultures
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Benchtop Ultracentrifuge [aka Ben]
Benchtop Beckman Coulter Optima MAX_XP Tabletop Ultracentrifuge
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BMG Clariostar [aka Clara]
The BMG Clariostar is a multifunctional spectrophotometer capable of measuring absorbance, fluorescence and luminscence at specific excitation and emission wavelengths. This model is also equipped with two injectors for multi step assays.
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BMG FLUOstar Omega [aka FLO]
FLUOstar Omega plate reader capable of reading absorbance, luminescence and fluorescence.
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Bond Rx Autostainer - IHC, IF, mIF
State of the art immunohistochemistry(IHC) autostainer. Capable of IHC, ISH, multiplex IHC/ISH, Akoya 6-plex Fluorescent whole tissue staining and RNAScope, with all its variants.
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Bruker Tims TOF Pro
Bruker tims TOF Pro mass spectrometer with Evosep One chromatography system or Bruker nanoElute chromatography system. A trapped ion mobility (TIMS) analyzer can be synchronized with a quadrupole mass filter to enable the highly efficient PASEF (Parallel Accumulation Serial Fragmentation acquisition) procedure with acquisition rates of 100 Hz.
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COY Hypoxia Chamber - Bacterial work [aka Imelda]
COY glove box which can be used for bacterial work Temperature controlled, CO2 and nitrogen gas controlled, No humidity control.
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Cyan ADP Yellow/Green
The CyAn ADP analyser is the next step in advanced digital processing
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CytoFLEX LX
A benchtop analyser for every application: Isolating and analysing blood or cultured cells, bacteria, algae, yeasts, microparticles and even nanoparticles like extracellular vesicles pose no challenge for this compact but powerful cytometer in any of its configurations.
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CytoFLEX LX (UV)
A benchtop analyzer for every application Isolating and analysing blood or cultured cells, bacteria, algae, yeasts, microparticles and even nanoparticles like extracellular vesicles pose no challenge for this compact but powerful cytometer in any of its configurations.
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CytoFLEX nano
The CytoFLEX nano Flow Cytometer is the first nanoscale flow cytometer that enables you to simultaneously detect particles as small as 40 nm* and characterize particles with precision thanks to its 6 channels of fluorescent measurement and ability to count via volumetric delivery.
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CytoFLEX S
A benchtop analyzer for every application: Isolating and analyzing blood or cultured cells, bacteria, algae, yeasts, microparticles and even nanoparticles like extracellular vesicles pose no challenge for this compact but powerful cytometer in any of its configurations.
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CytoFLEX SRT
CytoFLEX SRT Cell Sorter is a high speed cell sorter which includes innovative technologies that simplify setup and operation. The instrument has four lasers and up to 15-color detection to identify subtle differences between cells. Capable of complex sort logic with different combinations of sort settings for each of its four streams, including the ability to catch aborts of sort streams in alternate streams.
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Dako Autostainer Link 48
"The DAKO Autostainer Link 48 is used to automatically perform immunohistochemistry (IHC) on histological tissue sections. In general chromogens are used to visualise the staining but fluorophores can also be used (IF)."
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FACSAria IIIu Cell Sorter
This high-speed cell sorter (40,000 events/second) has 4 lasers: 488nm (blue), 561nm (green), 633nm (red) and 407nm (violet) for detection of FSC, SSC and up to 10 fluorescent parameters. It is able to sort 4 populations of cells at the same time and perform single cell cloning in well plate platforms with a 100% purity level and 95% viability.
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Fast Protein Liquid Chromatography (FPLC) [aka Felicia]
AKTA Prime Plus is an FPLC instrument.
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Fast Protein Liquid Chromatography (FPLC) [aka Finn]
AKTA Pure FPLC
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Fast Protein Liquid Chromatography(FPLC) [aka Fifi]
AKTA Go FPLC
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FLIM microscope
Microscope dedicated to fluorescent live imaging (FLIM), frequency domain. Integrated by Lambert. Optional: high-power high-resolution transmission light microscopy for live cells
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Floor standing Ultracentrifuge [aka Sam]
Floor standing Beckman Optima L-100 XPUltracentrifuge Max speed 100,000 rpm [802,400 x g] Rotors: 70 Ti Rotor- fixed angle, 8 X 39ml , 70,000rpm , 504,000 x g SW 32 Ti Rotor - Swinging bucket, 6 X 38.5 ml, 32,000, 175,000 x g SW 41 Ti Rotor, Swinging bucket, 6 X 13.2 ml, 41,000 rpm , 288,000 x g
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Floor Standing Ultracentrifuge [aka Zoë]
Floor Standing Beckman Coulter Optima XPN-100 Ultracentrifuge
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Freeze Dryer [aka Fonzie]
The freeze dryer can be used to dry water based samples only. This instrument cannot be used for drying solvents.
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FT-MTA03 Micromechanical Testing and Assembly System
System Capabilities Nanoindentation Micro Tensile Testing Stylus Profilometry Microstructure Analysis
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Gas Chromatograph (GC)- Mass Spectrometer(MS)
This GC-MS system consists of an Agilent 8890 GC system and 5977 C single quadrupole mass spectrometer, furthermore equipped with G7370B PAL3 Series II auto sampler systems.
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Illumina Nextseq 2000
The Nextseq 2000 is a high-throughput, short read sequencer that utilises Illumina's latest XLEAP-SBS Chemistry. The various flowcell options available allow researchers the scalability to deal with sequencing project sizes. Its conveniently linked to the Illumina Basespace Cloud for ease of run setup and data transfer and offers on-instrument secondary data analysis pipelines.
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Image Analysis PC
A powerful working station is available for all users for Image analysis. Several analytical software are pre-installed: FIJI, Imaris, AutoQuant, Ilastic, and ZenDesk.
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Invivo 2 400 Hypoxia Chamber [aka Gretel]
Hypoxia chamber with manual humidity control
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Invivo2 400 Hypoxia Chamber [aka Hansel]
Hypoxic chamber with automatic humidity control
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LCMS_Quant 500 [Metabolomics Core]
LC part: A SCIEX ExionLC™ Series UHPLC equipped with a degasser, dual pump, column oven, autosample Key features include:;UHPLC Performance; 190,000 PSI
Cooled Autosampler; Direct cooling, 4 to 40 degC; Temperature Controlled Column Oven; Room Temp. -10 deg C to 85 degC MS part: An SCIEX QTRAP 6500plus system;Key features include: Mass Range;Dual switchable mass range: up to 1250 Da or up to 2000 Da Features; IonDrive QJet, HED Detector Detector Type;IonDrive High Energy Detector+ -
Leica ACE 600 Glow Discharger/sputter coater
The Leica EM ACE600 Sputter Coater/Carbon coater/Glow discharger. Note: The high-vacuum device requires perfectly dry samples.
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Leica EM GP2 Plunge-freezer
Leica EM GP2 Grid Plunger is the device for the freeze fixation nanoparticles, viruses, or cell monolayers grown on TEM grids, in the liquid ethane at -180C.
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Leica EM PACT2 High-pressure freezer
High-pressure freezing (HPF) is a method of fixation of biological objects (cell culture, pieces of tissue, small animals like C.elegans, etc.) for electron- and correlative microscopy. HPF allows for immediate fixation without artifacts of chemical fixation.
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Leica UC6 Ultramicrotome
The Ultramicrotome Leica EM UC6 povides easy preparation of semi- and ultrathin sections as well as perfect, smooth surfaces of biological and industrial samples for TEM, SEM, AFM and LM examination.
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Leica UC7 Ultramicrotome
"The Ultramicrotome Leica EM UC7 provides easy preparation of semi- and ultrathin sections as well as perfect, smooth surfaces of biological and industrial samples for TEM, SEM, AFM and LM examination. "
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Li-COR CLx Western Blotting imaging system [LEX]
Li-COR Odyssey CLx is an updated Western Blotting, slide cell, imaging system that can be used with antibodies in the NIR range.
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LI-COR Western Blotting Imaging System [aka Clarke]
Li-COR Odyssey CLx is an updated Western Blotting, slide cell imaging system that can be used with antibodies in the NIR range.
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Lumen X - Cellink bioprinter
BIO X is a user-friendly and flexible bioprinter, providing the user with an unparalleled bioprinting experience. It can be used to automate 3D cell cultures, develop complex tissue constructs or test new drug compounds.
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Lumen X - Cellink bioprinter
Benchtop DLP based bioprinter. The LUMEN X is optimized to build solid hydrogel structure by beginning with a droplet of light-sensitive, liquid PhotoInk™ hydrogels in a vat.
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Luminex xMAP200
Luminex xMAP technology is built on proven, existing technology; flow cytometry, microspheres, lasers, digital signal processing and traditional chemistry that have been combined in a unique way.
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Lynx 6000 Superspeed centrifuge [Lola]
Lynx 6000 superspeed centrifuge with 3 Rotors and tubes Fiberlite F12-6x500 Fiberlite F14-6x250y Fiberlite F21-8x50y
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Mass Spectrometer [Metabolomics Core]
LC part: A SCIEX ExionLC;trade; Series UHPLC equipped with a degasser, dual pump, column oven, autosampler
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Microbeta 2
"The Microbeta is capable of measuring luminescence and radiometric samples in a plate format. "
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MS_Quant 500 [Metabolomics Core]
LC part: A SCIEX ExionLC™ Series UHPLC equipped with a degasser, dual pump, column oven, autosampler; Key features include:UHPLC Performance 190,000 PSI; Direct cooling, 4 to 40 deg C Temperature Controlled Column Oven Room Temp. -10 deg; C to 85 deg C MS part: An SCIEX QTRAP 6500plus system Key features include: Mass Range;Dual switchable mass range: up to 1250 Da or up to 2000 Da Features;IonDrive QJet, HED Detector Detector Type: Drive High Energy Detector
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Nanosight Data Analysis computer only
This computer can be used to analyse your data taken from the Nanosight Instrument.
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NanoSight NS3000
NanoSight NTA (Nanoparticle Tracking Analysis) is a well-established technique for characterization of bio and nanoparticles. By capturing the light scattered from particles undergoing Brownian motion, NTA provides particle-by-particle tracking for high-resolution size and concentration data.
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Olympus FV3000 confocal microscope
An inverted Olympus IX83 microscope, with 7 laser lines all over the visible spectrum (405, 445, 488, 515, 560, 595 and 640 nm). Best for multiplex confocal imaging of live cells and micro-organoids. Olympus Fluoview viewer software (free) is available to download from our server; Olympus folder. Installation instructions attached
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Quantstudio 5 qPCR System
"The Applied Biosystems QuantStudio 7 Flex is a high throughput Real-Time PCR instrument that detects and quantitates nucleic acid sequences.
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QuantStudio 7Flex qPCR System
The Applied Biosystems QuantStudio 7 Flex is a high throughput Real-Time PCR instrument that detects and quantitates nucleic acid sequences.
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Quorum Critical Point Dryer
The E3100 large chamber critical point dryer has been an industry standard for 30+ years and is used in numerous scanning electron microscopy (SEM) laboratories around the world. Primarily used for drying biological and other sensitive specimens. After drying, samples usually must be coated with a nanolayer of metal for conductivity, before being imaged in SEM.
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Sartorius Incucyte
The Sartorius Incucyte S3 is a microscope inside an incubator. It solves potential problems that may result from disturbing cells during the observation process rendering long-term kinetic imaging practical and easy.
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Scratch Wound Maker (Incucyte)
"Wound maker for scratch assays on 96 well plates. Imaging done on IncuCyte "
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Seahorse XF Mini Analyzer
Agilent Seahorse XF HS Mini Analyzers measure mitochondrial respiration and glycolysis as well as ATP production rate of live cells in an eight-well miniplate format. The quick and easy setup makes the Seahorse XF HS Mini Analyzer ideal for performing routine energy metabolism measurements of ex-vivo and other quantity-limited samples.
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Seahorse XF Pro Analyzer
Seahorse XF Pro Analyzer Agilent Seahorse XF Pro Analyzers measure the oxygen consumption (OCR) and extracellular acidification rate (ECAR/PER) of live cells in a 96-well format. The XF Pro Analyzer features better OCR precision at low rates, verified instrument performance and repeatability specifications, optimized temperature control, and is automation enabled.
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Sorval RC- 6 Plus [aka Sally]
Superspeed centrifuge with 3 rotors SLA-1500, F21 8x 50 y and F10s 6x500y
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Sorvall RC 26 plus
The Sorvall RC 26 plus is a superspeed centrifuge. Before using this centrifuge training is required by a Wing Manager.
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Sorvall Superspeed 5C RC plus centrifuge [aka Suzie]
Sorvall RC5C Plus is a refrigerated centrifuge with the following specifications: Speed Selection Range (rpm) 50 to 21,000 RPM; Speed Control Accuracy;plusmn;1% or 100 rpm, whichever is greater Maximum Relative Centrifugal Force; ;51,427 g Temperature Selection Range;-20 deg C to +40 deg C; Training is required by a Wing Manager before using this superspeed centrifuge
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Spectramax Microplate Reader
The Molecular Devices SpectraMax M3 Multi-Mode Microplate Reader is a dual-monochromator, multi-detection microplate reader with full spectral range detection for 6-, 12-, 24-, 48-, 96-, and 384-well microplates.
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Spinning disk confocal microscope
An inverted Nikon Ti microscope with lines of 405 nm, 488nm, and 560 nm, a Yokogawa spinning disk, a TIRF condenser, and two Andor EM CCD cameras, integrated by Andor Fusion. Applications: confocal;or TIRF microscopy of live cells.
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Stereo Microscope [aka Karl]
A basic low-magnification microscope with a high-resolution camera. Can be applied for basic imaging of relatively large and bulky objects that do not fit in other microscopes. Made in-house.
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Tecnai 20 TEM
Transmission Electron Microscopy (TEM) is used to investigate ultrastructure of thin samples (limited by the penetration of electron beam): flat cells, nano-particles, biological tissues embedded into polymers etc.
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Thermo Q-Exactive
"The Thermo Scientific Q Exactive is a hybrid quadrupole-Orbitrap mass spectrometer combining quadrupole precursor ion selection with high-resolution accurate-mass (HRAM) Orbitrap detection."
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Thermo Scientific Orbitrap Exploris 480
Thermo Scientific Orbitrap Exploris 480 with Vanquish Neo capillary chromatography system. This is a hybrid ESI-LCMS instrument that combines precursor ion selection using a quadrupole with high resolution high mass accuracy (HRAM) by Orbitrap.
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Transmission light microscope [aka Orina]
A dedicated transmission light microscope with a high-resolution power. Optional: differential interference contrast (DIC), dark filed microscopy, polarized microscopy.
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Tricarb Scintillation Counter [aka Trevor]
The Tri-Carb is a computer controlled bench top liquid scintillation counter for detecting small amounts of alpha, beta and gamma radioactivity.
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Vilber Fusion FX 7 [aka Valerie]
Chemiluminescent imager
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Vilber Fusion Fx 7 [aka Vinny]
The Vilber Fusion Fx 7 is a digital imager designed to allow visualisation and semi-quantification of both chemiluminescent and NIR fluorescent tagged proteins, e.g during Western Blotting.
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Vilber Fusion Fx7 [aka Vlad]
Fusion Fx 7 imager for chemiluminescent detection
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Zeiss AxioImager epi-fluorescent microscope for slides [aka John]
An epi-fluorescent microscope for imaging of slides. The microscope has a white LED light source, filter cubes for imaging of five separate fluorescent channels, and a modern low-noise CCD camera. Perfect for routine imaging and sample screening before confocal imaging. Suitable for 3D imaging if followed by deconvolution (training available in the Imaging core for no additional cost).
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Zeiss Axiovert 200 epi-fluorescent microscope for dishes [aka Suzi]
An inverted Zeiss Axiovert 200 microscope for imaging of live and fixed cells grown in culture dishes. For epi-fluorescent microscopy in the whole visible spectrum and near infra-red. Optional: transmission light microscopy. Optional: multi-positional time-lapse detection.
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Zeiss LSM 800 Airy
An upright confocal and Airy scan (ca. 50% better resolution than confocal, but slower scanning) microscope with four laser lines (405, 488, 560, and 640 nm) and a motorized stage.
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Zeiss Sigma 300 SEM
Zeiss Sigma 300 is a high-vacuum FEG-SEM electron microscope equipped with five detectors and a resolution of 1.2 nm, with the software for correlative light-electron microscopy.