Protocol for a multicentre randomised controlled trial of early and sustained prophylactic hypothermia in the management of traumatic brain injury.
Nichol A, Gantner D, Presneill J, Murray L, Trapani T, Bernard S, Cameron P, Capellier G, Forbes A, McArthur C, Newby L, Rashford S, Rosenfeld JV, Smith T, Stephenson M, Varma D, Walker T, Webb S, Cooper DJ. Crit Care Resusc. 2015 Jun;17(2):92-100. PMID: 26017126
Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial.
Nichol A, French C, Little L, Presneill J, Cooper DJ, Haddad S, Duranteau J, Huet O, Skrifvars M, Arabi Y, Bellomo R;EPO-TBI Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Trials. 2015 Feb 8;16:39. doi: 10.1186/s13063-014-0528-6. PMID: 25884605
A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis.
Kruger P1, Bailey M, Bellomo R, Cooper DJ, Harward M, Higgins A, Howe B, Jones D, Joyce C, Kostner K,McNeil J, Nichol A, Roberts MS, Syres G, Venkatesh B; ANZ-STATInS Investigators–ANZICS Clinical Trials Group. Am J Respir Crit Care Med. 2013 Apr 1;187(7):743-50. doi: 10.1164/rccm.201209-1718OC.
Long-term quality of life in patients with acute respiratory distress syndrome requiring extracorporeal membrane oxygenation for refractory hypoxaemia.
Hodgson CL, Hayes K, Everard T, Nichol A, Davies AR, Bailey MJ, Tuxen DV, Cooper DJ, Pellegrino V.
Crit Care. 2011;15(3):R133. doi: 10.1186/cc10249.
A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome.
Hodgson CL1, Tuxen DV, Davies AR, Bailey MJ, Higgins AM, Holland AE, Keating JL, Pilcher DV,Westbrook AJ, Cooper DJ, Nichol AD. Epub 2011 Jun 2. Crit Care. 2012 Oct 19;16(5):R202. doi: 10.1186/cc11811
Age of red blood cells and mortality in the critically ill.
Pettilä V, Westbrook AJ, Nichol AD, Bailey MJ, Wood EM, Syres G, Phillips LE, Street A, French C, Murray L, Orford N, Santamaria JD, Bellomo R, Cooper DJ; Blood Observational Study Investigators for ANZICS Clinical Trials Group. Crit Care. 2011;15(2):R116. doi: 10.1186/cc10142. Epub 2011 Apr 15.
Critical care services and 2009 H1N1 influenza in Australia and New Zealand.
ANZIC Influenza Investigators, Webb SA, Pettilä V, Seppelt I, Bellomo R, Bailey M, Cooper DJ, Cretikos M,Davies AR, Finfer S, Harrigan PW, Hart GK, Howe B, Iredell JR, McArthur C, Mitchell I, Morrison S, Nichol AD, Paterson DL, Peake S, Richards B, Stephens D, Turner A, Yung M. N Engl J Med. 2009 Nov 12;361(20):1925-34. doi: 10.1056/NEJMoa0908481. Epub 2009 Oct 8.
Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis.
Nichol AD1, O'Cronin DF, Howell K, Naughton F, O'Brien S, Boylan J, O'Connor C, O'Toole D, Laffey JG,McLoughlin P. Crit Care Med. 2009 Nov;37(11):2953-61. doi: 10.1097/CCM.0b013e3181b028ce.
Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury.
O'Croinin DF1, Nichol AD, Hopkins N, Boylan J, O'Brien S, O'Connor C, Laffey JG, McLoughlin P. Crit Care Med. 2008 Jul;36(7):2128-35. doi: 10.1097/CCM.0b013e31817d1b59.