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IVIS Spectrum CT
The IVIS Spectrum CT (PerkinElmer) is a bioluminescence and fluorescence optical system for in vivo and ex vivo imaging. The magnitude of the optical signal allows for longitudinal, non-invasive assessment of targets of interest via expression of a bioluminescent/fluorescent reporter gene or administration of a fluorescent or chemiluminescent probe. A wide range of commercially available targeted fluorescent probes facilitate in vivo imaging of angiogenesis, perfusion, inflammation, apoptosis and bone turnover. In addition, fluorescent in vivo imaging agents have been designed that activate florescence in the presence of various disease-associated proteases, e.g. metalloproteinases and cathepsins. Furthermore, dyes for labelling peptides, proteins, nanoparticles and antibodies are available.
Contact: (opens in a new window)Emer Conroy
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