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Scientific Advisory Board

Scientific Advisory Board

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Aedín Culhane, SAB Chair

Professor of Biomedical Sciences (Cancer Genomics), University of Limerick School of Medicine

Aedín is a Professor of Biomedical Sciences (Cancer Genomics) in the UL School of Medicine. She is a computational oncologist with expertise in multi-omics data integration, statistical genomics, clinical bioinformatics and genomics in oncology. She has over 20 years’ experience in cancer genomics, of which over 15 years were in the Dana-Farber Cancer Institute and Harvard TH Chan School of Public Health in Boston, USA. Her recent research focuses on algorithm development and integrative data of single cell molecular data in cancer to identify molecules that regulate and can be targeted during tumour development, progression, drug response and resistance. She is a member of the Human Cell Atlas (https://www.humancellatlas.org ) project. She is a leader in the Bioconductor (www.bioconductor.org) community, a global open source, open development software in R for genomics and an advocate for open source science.

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Steven Dubinett

Dean, David Geffen School of Medicine at UCLA, Vice Chancellor for the Clinical & Translational Science Institute

Steven M. Dubinett is Director of the UCLA Clinical & Translational Science Institute, Associate Vice Chancellor and Senior Associate Dean for Translational Research. He oversees the translation of UCLA biomedical discoveries into medical products and health interventions and is responsible for the efficient integration of the research infrastructure through the CTSI. He is a founding Executive Committee member of UC Biomedical Research Acceleration, Integration, and Development (UC BRAID), which integrates clinical and translational research across the University of California.

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Wolfgang Huber

Group Leader and Senior Scientist, EMBL

Wolfgang is an EMBL Senior Scientist, co-director of the Molecular Medicine Partnership Unit, a joint venture between the Medical Faculty of the University of Heidelberg and EMBL, co-head of the Theory Transversal Theme at EMBL, and co-head of EMBL’s Open Science and Responsible Research Assessment working groups.

He is a founding member of Bioconductor, a large, collaborative, international open-source software project for the analysis and comprehension of biological data. He is also a fellow of the International Society for Computational Biology, and an elected Member of the European Molecular Biology Organization (EMBO).

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Catherine Kelly

Director of Pharmacy, UPMC Ireland

Catherine has been part of the UPMC Whitfield team for 13 years holding roles as senior pharmacist, the hospital’s chief pharmacist and most recently Director of Pharmacy for UPMC Ireland.

As Director of Pharmacy for UPMC Ireland, Catherine continues to work with UPMC’s growing service lines, including medical oncology and cardiology, and supports the expansion of UPMC’s clinical research in collaboration with the University of Pittsburgh and other academic institutions in Ireland.

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Mark Lemmon

Alfred Gilman Professor and Chair of Pharmacology, Yale School of Medicine

Mark is the David A. Sackler Professor of Pharmacology, Co-Director of the Yale Cancer Biology Institute, and Associate Director for Basic Science of the Yale Cancer Center. His laboratory links studies of mechanistic and structural aspects of signalling by growth factor receptors (especially EGF receptor) in normal and disease states with cellular and clinical studies. His best known recent contributions include explanation of the structural bases for allostery and biased agonism in the EGF receptor and exploiting structural understanding to understand and target aberrant growth factor receptor signalling in cancer. Mark was awarded the Dorothy Crowfoot Hodgkin Award of the Protein Society in 2012 and was elected as a Fellow of the Royal Society in 2016.

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Jan Molenaar

Prof. Dr. and Principal Investigator, Princess Maxima Centre for Pediatric Oncology

The Molenaar group aims to develop new treatment options for pediatric cancer. We do this by connecting basic biological research to immuno- as well as targeted therapies. New therapeutic options are eventually applied in clincal trials through our precision medicine program. Our translational work has a strong focus on neuroblastoma tumors.

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Luke O'Neill

Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin

Luke is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O'Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was recently acquired by Roche.

Luke also has a passion for communicating science to the public. He has a weekly radio slot on the Pat Kenny show on Newstalk. In 2018 he published with Gill the best-selling ‘Humanology: a scientist’s guide to our amazing existence’ and in 2019 Gill published ‘The Great Irish Science Book’, a Science book for 10-12 year olds. His latest book, also published by Gill is called ‘Never Mind the B#ll*cks Here’s the Science’.

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Jesper Olsen

Professor, Deputy Head of Novo Nordisk Foundation Center for Protein Research (CPR) at University of Copenhagen

Jesper studied Analytical Chemistry at the University of Southern Denmark in Odense, and after two years as a Staff Scientist at MDS Proteomics Inc., he returned to the University and obtained his PhD in Biochemistry and Molecular Biology in the Laboratory of Matthias Mann. He spent 4 years as a Post-doctoral Fellow at the Max Planck Institute for Biochemistry in Munich. In 2009, Prof. Olsen was recruited back to Denmark to head a group at the newly established Novo Nordisk Foundation Center for Protein Research (CPR) at University of Copenhagen. In 2012, he was promoted to Vice Director of CPR and in 2014 Full Professor. Prof. Olsen’s group is developing mass spectrometry-based proteomics methods with a specific focus on quantitative phosphoproteomics technologies to study time-resolved cell signaling pathways on a global scale in cells and tissues.

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Samra Turajlic

Chief Investigator of translational studies into melanoma and kidney cancer (TRACERx) at the Francis Crick Institute

Samra is the Chief Investigator of translational studies into melanoma and kidney cancer, and her research goal is to develop an evolutionary understanding of cancer for patient benefit. She is a member of the NCRI Bladder and Renal Cancer Clinical Studies Group, ESMO Faculty member for genitourinary cancers; and Scientific Committee member for ESMO, Molecular Analysis for Personalised Therapy, Kidney Cancer Association, and EORTC-NCI-AACR Symposia. She is a Trustee of the Kidney Cancer Support Network and a Senior Editor at Macmillan Cancer Support. Dr Turajlic receives research funding from CRUK, Rosetrees Trust, the Royal Marsden Cancer Charity, and the RMH/ICR Biomedical Research Centre, among others.

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Systems Biology Ireland

University College Dublin, Belfield, Dublin 4, Ireland
T: +353 1 716 6331 | E: sbiadmin@ucd.ie